Clinical and coronary angiographic features of young women with acute myocardial infarction
10.3760/cma.j.issn.0253-3758.2012.03.010
- VernacularTitle:青年女性急性心肌梗死的危险因素及冠状动脉病变特点
- Author:
Zhao LI
1
;
Zhi-Zhong LI
;
Yu-Long GAO
;
Ying TAO
;
Su WANG
;
Qian WANG
;
Chang-Sheng MA
;
Xin DU
Author Information
1. 首都医科大学附属北京安贞医院
- Keywords:
Myocardial infarction;
Adolescent;
Risk factor;
Coronary angiography
- From:
Chinese Journal of Cardiology
2012;40(3):225-230
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical and coronary angiographie features of young women ( ≤44 years) with acute myocardial infarction (AMI).Methods Clinic and coronary angiographic features were compared among 57 young women with AMI and 60 non-CHD young women,78 young men with AMI and 80 elderly women with AMI were included,all patients were admitted to hospital from June 2003 to December 2010 and underwent coronary angiography.Body mass index (BMI),smoking history,familial history of early coronary artery disease,essential hypertension,type 2 diabetes mellitus,hyperlipidemia,serum uric acid (UA),menopause,lipids,total bilirubin (TBil),direct bilirubin (DBil),hemoglobin (Hb),red cell distribution width (RDW),fasting blood glucose (FBG) were measured.Results (1)Prevalence of essential hypertension,hypertriglyceridemia and levels of fasting blood glucose,triglyceride,serum uric acid were significantly higher while high density lipoprotein cholesterol,and hemoglobin were significantly lower in young women with AMI group than in age-matched non-CHD control group ( all P ＜0.05). (2) Logistic regression analysis showed that essential hypertension (OR =23.187),lower hemoglobin level ( OR =1.010) and uric acid ( OR =1.040) were independent risk factors for young women with AMI (all P ＜ 0.05 ).(3) Coronary angiography revealed normal coronary finding in 6 cases,singlevessel disease in 35 cases (26 cases with lefi anterior descending artery disease) and two-vessel disease in 12 patients.The ratio of single vessel disease involved lefi anterior descending artery in young women was higher than that of young men and old women with AMI ( all P ＜ 0.05 ).Conclusion Essential hypertension,lower hemoglobin and uric acid are risk factors of young women with AMI. Single vessel coronary disease is the most common coronary angiographic feature of young women with AM1.
