Recent advances of synthetic biology for production of functional ingredients in Chinese materia medica.

Author: Xin-Yao SU ¹ ; Jian-Ping XUE ² ; Cai-Xia WANG ¹
Author Information

1. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
2. Huaibei Normal University, Huaibei 235000, China.
Publication Type:Journal Article
Keywords: fuctional ingredients; synthetic biology
From: China Journal of Chinese Materia Medica 2016;41(22):4150-4157
CountryChina
Language:Chinese
Abstract: The functional ingredients in Chinese materia medica are the main active substance for traditional Chinese medicine and most of them are secondary metabolites derivatives. Until now,the main method to obtain those functional ingredients is through direct extraction from the Chinese materia medica. However, the income is very low because of the high extraction costs and the decreased medicinal plants. Synthetic biology technology, as a new and microbial approach, can be able to carry out large-scale production of functional ingredients and greatly ease the shortage of traditional Chinese medicine ingredients. This review mainly focused on the recent advances in synthetic biology for the functional ingredients production.