Research Progress of Cell Immunotherapy in Treatment of Hematological Malignancies-Review.
10.7534/j.issn.1009-2137.2017.03.055
- VernacularTitle:细胞免疫疗法对血液系统恶性肿瘤治疗作用的研究进展
- Author:
Wei ZHANG
1
;
Hong-Mei JING
1
;
Ji-Jun WANG
1
;
Xiao-Yan KE
2
,
3
Author Information
1. Department of Hematology, Peking University Third Hospital, Beijing 100191, China.
2. Department of Hematology, Peking University Third Hospital, Beijing 100191, China. E-mail: xykbysy@
3. com.
- Publication Type:Journal Article
- From:
Journal of Experimental Hematology
2017;25(3):941-946
- CountryChina
- Language:Chinese
-
Abstract:
Cell immunotherapy, as an important mean of tumor therapy, infuses a large number of immune effector cells amplified in vitro to the patients, resulting in the anti-tumor effect. There have been a series techniques of cell immunotherapy, including T lymphocyte therapy, dendritic cell-based immune cell therapy, natural killer cell therapy, gamma delta T cell therapy and so on. The preparation and culture conditions, anti-tumor mechanism, target cells etc of these immune cells are not the same, the each with its advantages and disadvantages. Many clinical studies have showed that the patients with a variety of tumors including hematological malignancies, who adopted cell immuno-therapy, had the prolonged survival, an improved quality of life, and with the less adverse reactions. This review summarizes the available data on the characteristics of different cell immunotherapies and their application in hematological malignancies.
