Advances in the study of ginsenoside compound K.
- Author:
Wei ZHOU
1
;
Pei ZHOU
Author Information
1. School of Pharmacy, Fudan University, Shanghai 200032, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Anti-Inflammatory Agents;
pharmacology;
Antineoplastic Agents, Phytogenic;
pharmacology;
Apoptosis;
drug effects;
Cell Line, Tumor;
Ginsenosides;
biosynthesis;
pharmacokinetics;
pharmacology;
Humans;
Liver;
drug effects;
Panax;
metabolism;
Plants, Medicinal;
metabolism;
Protective Agents;
pharmacology;
Tissue Distribution
- From:
Acta Pharmaceutica Sinica
2007;42(9):917-923
- CountryChina
- Language:Chinese
-
Abstract:
Ginsenoside compound K is the main metabolite of protopanaxadiol type ginseng saponins in intestine after oral administration and also is the major form of protopanaxadiol saponins absorbed to the body. Recently, ginsenoside compound K has received increasing attention, because in vivo or in vitro various biological actions of anticancer, hepatoprotective and anti-inflammatory etc, have shown to be mediated by this metabolite. In this paper, the studies of preparation, bioactivities, absorption, distribution and pharmacokinetics of compound K were reviewed in detail.
