A Case of IgA Nephropathy Associated with Systemic Lupus Erythematosus.
10.4078/jkra.2009.16.1.54
- Author:
So Young BANG
1
;
Gheun Ho KIM
;
Dong Ho SHIN
;
Moon Hyang PARK
;
Jae Bum JUN
Author Information
1. Division of Rheumatology, Department of Internal Medicine, The Hospital for Rheumatic Diseases, Hanyang University College of Medicine, Seoul, Korea. junjb@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
IgA nephropathy;
Systemic lupus erythematosus;
Non-tuberculous mycobacterium
- MeSH:
Adult;
Antigen-Antibody Complex;
Biopsy;
Female;
Glomerulonephritis, IGA;
Humans;
Immunoglobulin A;
Lung Diseases;
Lupus Erythematosus, Systemic;
Lupus Nephritis;
Nephritis
- From:The Journal of the Korean Rheumatism Association
2009;16(1):54-58
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Renal involvement is frequently seen in patients with systemic lupus erythematosus (SLE). The occurrence of non-lupus nephritis, and especially IgA nephropathy, in SLE patients has rarely been reported. We describe here the case of a 30-year-old woman who had systemic lupus erythematosus and nontuberculous mycobacterial lung disease, and her biopsy of a renal lesion was unexpectedly diagnostic of IgA nephropathy. Although both IgA nephropathy and lupus nephritis are immune complex mediated diseases, their laboratory and histopathologic findings and the extra-renal clinical manifestations are different and these all support a different pathogenesis for the 2 diseases. Renal biopsy plays a crucial role in identifying and diagnosing renal lesions, which may have prognostic and therapeutic implications that are distinct from those of lupus nephritis. In conclusion, performing a renal biopsy in SLE patients who have urinary abnormalities is important since a correct diagnosis would permit the most appropriate treatment to be started and so avoid unnecessary immunosuppressive treatments.
