A new coumarin glycoside from Glehnia littoralis.
- Author:
Ya ZHAO
1
;
Zhong YUAN
Author Information
1. Department of Analysis of Traditional Chinese Medicine, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
- Publication Type:Journal Article
- MeSH:
Apiaceae;
chemistry;
Coumarins;
chemistry;
isolation & purification;
Deoxyadenosines;
chemistry;
isolation & purification;
Disaccharides;
chemistry;
isolation & purification;
Furocoumarins;
chemistry;
isolation & purification;
Glycosides;
chemistry;
isolation & purification;
Molecular Structure;
Plant Roots;
chemistry;
Plants, Medicinal;
chemistry;
Thionucleosides;
chemistry;
isolation & purification
- From:
Acta Pharmaceutica Sinica
2007;42(10):1070-1073
- CountryChina
- Language:Chinese
-
Abstract:
To study the chemical constituents from Glehnia littoralis, macroreticular resin column chromatography, repeated column chromatography on Sephadex LH-20 and reverse phase ODS were used to isolate the compounds whose structures were elucidated based on spectroscopic data (ESI-MS, 1D and 2D NMR). A new coumarin glycoside was isolated and identified as: bergaptol 5-O-beta-D-gentiobioside (1), along with eight known compounds: (7R, 8S)-dehydrodiconiferylalcohol-4, 9-di-O-beta-D-glucoside (2), cirtrusin A (3), (-)-seco-isolariciresinol 4-O-beta-D-glucopyranoside (4), baihuaqianhuside (5), xanthotoxol 8-O-beta-D-glucopyranoside (6), 5'-methylthioadenosine (7), adenosine (8), L-tryptophan (9). Compound 1 is a new coumarin glycoside, compounds 2 and 7 were isolated from this genus for the first time.
