Clinical study of effect of tianzhi granule on senile vascular demetia.
- Author:
Gui-you DU
1
;
Xin-cheng ZHU
;
Jian-jun ZHAO
;
Jian WANG
;
Jin-zhou TIAN
;
Xian-feng LIU
;
Hui-ping ZHI
;
Yong ZHAO
;
Chun-yu CAO
;
Hai-feng CUI
;
Xiu-rong WANG
;
Chun-ying ZHANG
Author Information
- Publication Type:Clinical Trial
- MeSH: Aged; Blood Viscosity; drug effects; Dementia, Vascular; blood; drug therapy; Double-Blind Method; Drug Combinations; Drugs, Chinese Herbal; isolation & purification; therapeutic use; Erythrocyte Aggregation; drug effects; Erythrocyte Deformability; drug effects; Humans; Medicine, Chinese Traditional; Middle Aged; Multicenter Studies as Topic; Phytotherapy; Plants, Medicinal; chemistry; Recognition (Psychology); drug effects
- From: China Journal of Chinese Materia Medica 2003;28(1):73-77
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the clinical effect of Tianzhi Granule (TZK) on senile vascular dementia (VaD), which is classified as sthenia of liver-yang.
METHODTwo hundred VaD patients were treated with TZK (0.5 g/bag), which was taken one bag each, three times a day. The treatment course was one month and they were treated for rwo courses.
RESULTTZK could remarkably increase gnosia and activity, with no striking difference from that of positive control group (P > 0.05). Simultaneously, TZK could significantly improve the clinical syndrome of traditional Chinese medicine and viability. It could also drastically reduce the whole blood and plasma viscosity and improve erythrodegeneration and abnormality of aggregation index in the abnormal blood viscosity patients.
CONCLUSIONTMC has certain effects on senile VaD.
