Effect of blood lipid on the change of brachial-ankle pulse wave velocity among prehypertensive population
10.3760/cma.j.issn.0254-6450.2014.09.020
- VernacularTitle:血脂水平对血压正常高值人群脉搏波传导速度的影响
- Keywords:
[Key words] Abnormal blood lipid;
Pulse wave velocity;
Lipoprotein ration;
Prehypertension;
Arterial stiffness
- From:
Chinese Journal of Epidemiology
2014;35(9):1058-1061
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of blood lipid and lipoprotein ratios on the change of brachial-ankle pulse wave velocity (baPWV) among prehypertensive subjects.Methods 11 611 subjects with normal blood pressure (BP) were divided into two groups,which was one with optimal blood pressure (B P ＜ 120/80 mmHg) and the other with prehypertension (BP:120-139/80-89 mmHg).Height,weight,baPWV,fasting blood-glucose,TC,TG,LDL-C and HDL-C were detected.Results The abnormal rate ofbaPWV in prehypertension group was obviously higher than that in the optimal blood pressure group.For optimal blood pressure group,the abnormality of TG,TC,LDL-C,TC/HDL-C as well as LDL-C/HDL-C,caused the increase of baPWV significantly (P＜0.001).For prehypertensive group,the abnormality of TC and LDL-C caused the significant increase of baPWV (P＜0.001).Results from logistic regression analysis showed that except for age,BMI and fasting blood-glucose,TC/HDL-C increasing was the independent risk factor in optimal blood pressure group,while TG increasing was for the prehypertension group.Conclusion With different normal BP level,both abnormality of blood lipid and lipoprotein ratio were the independent risk factors for baPWV increasing.
