Effects of noninvasive positive pressure ventilation on patients with arrhythmia complicated by sleep apnea syndrome
10.3760/cma.j.issn.0253-3758.2013.09.006
- VernacularTitle:无创正压通气对睡眠呼吸暂停综合征合并心律失常的影响
- Keywords:
Sleep apnea syndrome;
Arrhythmia;
Positive-pressure respiration
- From:
Chinese Journal of Cardiology
2013;41(9):747-750
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of noninvasive positive pressure ventilation (NPPV) in treatment of patients with arrhythmia complicated by sleep apnea syndrome (SAS).Methods One hundred and thirty-five arrhythmia patients with polysomnography diagnosed SAS were randomly divided into NPPV group (69 cases) and control group (66 cases),the NPPV group was treated with standard medications and NPPV,and the control group was treated with standard medications.SAS related parameters were compared between the groups after 3 months therapy.Results (1) Epworth sleepiness scale (ESS) score,apnea-hypopnea index (AHI) and arousal index were significantly lower (8.25±5.41 vs.4.08±3.43,39.95±7.32 vs.4.71±1.80 and 39.69±4.40 vs.15.20±2.05,P＜0.01) while not rapid eye movement (NREM) Ⅲ and rapid eye movement stage of sleep time and lowest pulse oxygen saturation (LSaO2) were significantly higher in NPPV group than in control group [(4.53 ±2.10)％ vs.(16.78 ±2.59)％,(8.37 ± 1.380)％ vs.(15.25 ± 1.41)％,(77.15 ±6.72)％ vs.(93.35 ± 2.03)％,P ＜ 0.01] after 3 months therapy.(2) Incidence of Sinus bradycardia,sinus tachycardia,sinus arrest,atrial premature beats,ventricular premature beats,paroxysmal atrial tachycardia,paroxysmal ventricular tachycardia,atrial fibrillation,Ⅱ-Ⅲ degree atrioventricular block,ST-T segment changes were reduced from 57.4％,44.4％,7.4％,20.4％,13.0％,36.5％,12.0％,8.3％,37.0％,53.7％ to 4.6％,1.9％,0.0％,3.7％,2.8％,7.0％,0.9％,0.0％,1.9％,4.6％ (allP＜0.05) and the total number of arrhythmias happened at night were significantly lower (all P ＜ 0.05) while the heart rate variability (HRV) were significantly higher (P ＜ 0.01) in NPPV group than in control group; AHI was positively while LSaO2 was negatively correlated with the total night arrhythmia number (P ＜ 0.01).Conclusion Noninvasive positive pressure ventilation is an effective therapy strategy for treating patients with arrhythmia complicated by sleep apnea syndrome.
