Relativity analysis of chronic hepatitis B virus genotype and clinical pathology
10.3760/cma.j.issn.1003-9279.2008.02.012
- VernacularTitle:慢性乙型肝炎病毒基因型与临床病理相关性分析
- Author:
Wei-Ping HE
1
;
Jin-Hua HU
;
Hui-Fen WANG
Author Information
1. 解放军第302医院
- Keywords:
Hepatitis B virus;
Genotype;
Liver function;
Liver/pathology
- From:
Chinese Journal of Experimental and Clinical Virology
2008;22(2):116-118
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between chronic hepatitis B virus genotypes and clinical pathology. Methods HBV genotype was determined in 92 cases with chronic hepatitis B patients and the relationship between HBV genotypes and clinical, serological and histological data of the patients was analyzed.Results Sixteen cases were infected with HBV genotype B (17.4%), 71 with genotype C (77,2%), 3 with HBV classified as genotype B + C (3.2%) and in 2 (2.2%) cases HBV genotype was not confirmed. ALT level and HBV DNA load log value were (82.6± 82) U/L, (84.7 ± 71.5) U/L and (5.8 ± 1.4), (5.9 ± 1.5)respectively in genotypes B and C patients, in 8 cases of genotype C group liver cirrhosis was diagnosed, but no statistical significance was seen. Conclusion No significant differences in clinical, serological or histological data were detected between genotypes B and C patients.
