Four Years Prospective Study of Natural History of Atopic Dermatitis Aged 7~8 Years at an Individual Level: A Community-Based Survey by Dermatologists' Skin Examination in Childhood.
- Author:
Young Jee KIM
1
;
Sook Jung YUN
;
Jee Bum LEE
;
Seong Jin KIM
;
Young Ho WON
;
Seung Chul LEE
Author Information
- Publication Type:Original Article
- Keywords: Age-dependent change; Childhood atopic dermatitis; Dermatologists' skin examination; Spontaneous remission
- MeSH: Child; Dermatitis, Atopic*; Follow-Up Studies; Humans; Korea; Natural History*; Prevalence; Prospective Studies*; Remission, Spontaneous; Skin*
- From:Annals of Dermatology 2016;28(6):684-689
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: The age-dependent change in atopic dermatitis (AD) at an individual level has mostly performed in a hospital-setting. OBJECTIVE: We evaluated the age-dependent change of AD symptoms at an individual level in a community-setting. METHODS: For the diagnostic accuracy, all participants of schoolchildren were received skin examination by dermatologists (twice a year for the same group), instead of questionnaire-based surveys. For this study, sequential check-ups of 273 elementary school children, aged 7~8 years, were performed for 4 years up to the age of 10~11 years. RESULTS: Among the 47 AD children, who had been diagnosed as having AD at the first-year check-up, spontaneous remission was detected in nine children during the follow-up periods (remission rate of 19.1%). As a consequence, the one-year AD prevalence was decreased by 5.9% in the elementary schoolchildren over four years. Unexpectedly, late onset (after 8 years of age) AD was observed in 21.7% of AD children. There was no statistically significant relationship between spontaneous remission and host factors including sex and family history of atopic diseases. CONCLUSION: We observed that 19.1% of AD children in the age group of 7~11 years showed spontaneous remission based on skin examination by dermatologists. There might be an increase in the prevalence of late onset AD in Korea.
