An update of biomarkers in prostate cancer tissue.
- Author:
Yong-Chuan WANG
1
;
Shu-Jie XIA
Author Information
1. Department of Urology, The First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200080, China.
- Publication Type:Journal Article
- MeSH:
Biomarkers, Tumor;
Early Diagnosis;
Humans;
Male;
Methylation;
Prostatic Neoplasms;
diagnosis;
pathology
- From:
National Journal of Andrology
2009;15(11):1039-1043
- CountryChina
- Language:Chinese
-
Abstract:
The development of biomarkers for prostate cancer screening, detection and prognosis has greatly decreased the mortality of this disease. Recently, some new views on such biomarkers as PSMA, CK34betaE12, p63, AMACR, Pca-24, hTERT, DD3, Annexin A3 and GSTP1 methylation in prostate cancer tissue have been re-identified and investigated. Future research should focus on the combined screening of multiple biomarkers and discovery of new ones, which may possibly improve the sensitivity, specificity and accuracy of the early detection of prostate cancer.
