Pathological characteristics and clinical significance of macrochilia secondary to venular malformation
10.3760/cma.j.issn.1002-0098.2010.04.005
- VernacularTitle:微静脉畸形伴唇肥大畸形的病理特点及临床意义
- Author:
Wei WANG
1
;
Xiao-Xi LIN
;
Gang MA
;
Wei LI
;
Xiao-Jie HU
;
Hui CHEN
Author Information
1. 上海市皮肤病性病医院
- Keywords:
Macrochilia;
Venular malformations;
Hamartomatous changes
- From:
Chinese Journal of Stomatology
2010;45(4):211-213
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the histologic characteristics of macrochilia secondary to portwine stain and to elucidate the possible mechanism.Methods Twenty-one cases of macrochilia secondary to venular malformation were included and the histology of the lesions was observed by light microscope.Results Histological examination revealed vascular abnormalities and a number of widely distributed hamartomatous changes in macrochilia secondary to venular malformation.The average vessel diameter is (39.8±15.7)μm.The degree of hamartomatous change:mild(1 case),moderate(7 cases)and severe(13 cases).Conclusions The complex hamartomatous changes suggest a genetically determined,multilineage developmental field defect in the pathogenesis of venular malformation.
