Antimicrobial activity of some essential oils against oral multidrug-resistant Enterococcus faecalis in both planktonic and biofilm state.

Fethi BENBELAÏD; Abdelmounaïm KHADIR; Mohamed Amine ABDOUNE; Mourad BENDAHOU; Alain MUSELLI; Jean COSTA

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Antimicrobial activity of some essential oils against oral multidrug-resistant Enterococcus faecalis in both planktonic and biofilm state.

Author: Fethi BENBELAÏD ¹ ; Abdelmounaïm KHADIR ¹ ; Mohamed Amine ABDOUNE ¹ ; Mourad BENDAHOU ¹ ; Alain MUSELLI ² ; Jean COSTA ²
Author Information

1. Laboratory of Applied Microbiology in Food, Biomedical and Environment (LAMAABE), Aboubekr Belkaïd University, PO Box 119, 13000 Tlemcen, Algeria.
2. Laboratory of Natural Products Chemistry, University of Corsica, UMR CNRS 6134, Campus Grimaldi, BP 52, 20250 Corte, France.
Publication Type:Journal Article
Keywords: Bacterial infections; Biofilm; Enterococcus faecalis; Essential oils; Multidrug-resistance
From:Asian Pacific Journal of Tropical Biomedicine 2014;4(6):463-472
CountryChina
Language:English
Abstract:
OBJECTIVETo evaluate some essential oils in treatment of intractable oral infections, principally caused by biofilm of multidrug-resistant Enterococcus faecalis (E. faecalis), such as persistent endodontic infections in which their treatment exhibits a real challenge for dentists.
METHODSTen chemically analyzed essential oils by gas chromatography-mass spectrometry were evaluated for antimicrobial activity against sensitive and resistant clinical strains of E. faecalis in both planktonic and biofilm state using two methods, disk diffusion and broth micro-dilution.
RESULTSStudied essential oils showed a good antimicrobial activity and high ability in E. faecalis biofilm eradication, whether for sensitive or multidrug-resistant strains, especially those of Origanum glandulosum and Thymbra capitata with interesting minimum inhibitory concentration, biofilm inhibitory concentration, and biofilm eradication concentration values which doesn't exceed 0.063%, 0.75%, and 1.5%, respectively.
CONCLUSIONSFindings of this study indicate that essential oils extracted from aromatic plants can be used in treatment of intractable oral infections, especially caused by biofilm of multidrug-resistant E. faecalis.