A new 8-O-4' neolignan from Glehnia littoralis.
- Author:
Li-li WANG
1
;
Wei-xue KONG
;
Zhong YUAN
Author Information
1. Department of Analysis of Traditional Chinese Medicine, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
- Publication Type:Journal Article
- MeSH:
Apiaceae;
chemistry;
Butylene Glycols;
chemistry;
isolation & purification;
Caffeic Acids;
chemistry;
isolation & purification;
Lignans;
chemistry;
isolation & purification;
Molecular Structure;
Plants, Medicinal;
chemistry
- From:
Acta Pharmaceutica Sinica
2008;43(10):1036-1039
- CountryChina
- Language:Chinese
-
Abstract:
To study the chemical constituents from Glehnia littoralis, macroreticular resin column chromatography, repeated column chromatography on Sephadex LH-20 and reverse phase ODS were used to isolate the compounds whose structures were elucidated based on spectroscopic data (ESI-MS, 1D and 2DNMR). From EtOAc-soluble fraction of the ethanol extracts, a new 8-O-4' neolignan was isolated and named as glehlinoside D (1), along with five known compounds: (-)-secoisolariciresinol (2), ferulic acid (3), caffeic acid (4), vanillic acid (5) and syringin (6). Compound 1 is a new 8-O-4' neolignan.
