A Case of Guttate Psoriasis after Treatment with IFN-alpha.
- Author:
Jung Eun KIM
1
;
Dae Hyun KIM
;
Hyung Dong KIM
;
Sung Yul LEE
;
Jong Suk LEE
;
Young Lip PARK
;
Kyu Uang WHANG
Author Information
1. Department of Dermatology, College of Medicine, Soonchunhyang University, Seoul, Korea. snolomas@hosp.sch.ac.kr
- Publication Type:Case Report
- Keywords:
Guttate psoriasis;
Interferon alpha
- MeSH:
Female;
Humans
- From:Korean Journal of Dermatology
2010;48(4):296-299
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Psoriasis is considered to be an autoimmune disease of abnormal keratinocyte proliferation induced by T lymphocytes. An association with several cytokines has been suggested. Interferon (IFN) is a cytokine secreted by virus-infected cells and has the ability to prevent further infection of cells that were exposed to it. It has therefore been used as a therapeutic agent for many chronic viral diseases such as chronic hepatitis C. Recently, however, IFN has also been considered to be a triggering factor in the development of psoriasis. We describe an 18-year-old woman presenting with guttate psoriasis, who suffered soft tissue sarcoma and underwent chemotherapy containing IFN-alpha. This is possibly the first case of guttate psoriasis associated with IFN-alpha in the Korean literature.
