Volumetric quantification of bone-implant contact using micro-computed tomography analysis based on region-based segmentation.
- Author:
Sung Won KANG
1
;
Woo Jin LEE
;
Soon Chul CHOI
;
Sam Sun LEE
;
Min Suk HEO
;
Kyung Hoe HUH
;
Tae Il KIM
;
Won Jin YI
Author Information
- Publication Type:Original Article
- Keywords: Absorbable Implants; Osseointegration; X-Ray Microtomography; Computer-Assisted Image Processing
- MeSH: Absorbable Implants; Absorption; Image Processing, Computer-Assisted; Osseointegration; X-Ray Microtomography
- From:Imaging Science in Dentistry 2015;45(1):7-13
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: We have developed a new method of segmenting the areas of absorbable implants and bone using region-based segmentation of micro-computed tomography (micro-CT) images, which allowed us to quantify volumetric bone-implant contact (VBIC) and volumetric absorption (VA). MATERIALS AND METHODS: The simple threshold technique generally used in micro-CT analysis cannot be used to segment the areas of absorbable implants and bone. Instead, a region-based segmentation method, a region-labeling method, and subsequent morphological operations were successively applied to micro-CT images. The three-dimensional VBIC and VA of the absorbable implant were then calculated over the entire volume of the implant. Two-dimensional (2D) bone-implant contact (BIC) and bone area (BA) were also measured based on the conventional histomorphometric method. RESULTS: VA and VBIC increased significantly with as the healing period increased (p<0.05). VBIC values were significantly correlated with VA values (p<0.05) and with 2D BIC values (p<0.05). CONCLUSION: It is possible to quantify VBIC and VA for absorbable implants using micro-CT analysis using a region-based segmentation method.
