A Case of IgG4-Related Disease Presenting as Massive Pleural Effusion and Thrombophlebitis.
10.4046/trd.2014.76.4.179
- Author:
Jong Hyun CHOI
1
;
Jae Kyeom SIM
;
Jee Youn OH
;
Eun Joo LEE
;
Gyu Young HUR
;
Seung Heon LEE
;
Sung Yong LEE
;
Je Hyeong KIM
;
Sang Yeub LEE
;
Chol SHIN
;
Jae Jeong SHIM
;
Kwang Ho IN
;
Kyung Ho KANG
;
Kyung Hoon MIN
Author Information
1. Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. minkyunghoon@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Immunoglobulin G;
Pleural Effusion;
Thrombophlebitis
- MeSH:
Immunoglobulin G;
Immunoglobulins;
Lung;
Mediastinum;
Plasma Cells;
Pleura;
Pleural Effusion*;
Thrombophlebitis*
- From:Tuberculosis and Respiratory Diseases
2014;76(4):179-183
- CountryRepublic of Korea
- Language:English
-
Abstract:
Immunoglobulin (Ig) G4-related disease is a recently recognized systemic fibroinflammatory condition characterized by a lymphoplasmacytic infiltrate rich in IgG4-positive plasma cells with elevated circulating levels of IgG4. The disease can either be localized to one or two organs, or present as diffuse multi-organ disease. Furthermore, lesions in different organs can present simultaneously or metachronously. In the pulmonary manefestations, lesions associated with IgG4-related disease have been described in the lung parenchyma, airways and pleura, as well as the mediastinum. We report a case of IgG4-related disease presenting as massive pleural effusion and thrombophlebitis.
