Primary Intracranial Leptomeningeal Melanomatosis.
10.3340/jkns.2015.58.6.554
- Author:
Do Hyoung KIM
1
;
Chan Young CHOI
;
Chae Heuck LEE
;
Mee JOO
Author Information
1. Department of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Inje University, Goyang, Korea. cychoi@paik.ac.kr
- Publication Type:Case Report
- Keywords:
Primary;
Melanoma;
CNS;
Subarachnoid hemorrhage;
Leptomeninges
- MeSH:
Aged;
Biopsy;
Brain;
Cerebrospinal Fluid;
Conjunctiva;
Female;
Headache;
Humans;
Magnetic Resonance Imaging;
Melanoma;
Nevus;
Prognosis;
Skin;
Subarachnoid Hemorrhage;
Temporal Lobe
- From:Journal of Korean Neurosurgical Society
2015;58(6):554-556
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary intracranial malignant melanoma is a very rare and highly aggressive tumor with poor prognosis. A 66-year-old female patient presented a headache that had been slowly progressing for several months. A large benign pigmented skin lesion was found on her back. A brain MRI showed multiple linear signal changes with branching pattern and strong enhancement in the temporal lobe. The cytological and immunohiostochemical cerebrospinal fluid examination confirmed malignant melanoma. A biopsy confirmed that the pigmented skin lesion on the back and the conjunctiva were benign nevi. We report a case of primary intracranial malignant melanoma and review relevant literatures.