Treatment of Aplasia Cuti Congenita Using Allogenic Dermal matrix and Cultured Epithelial Autograft : A Case Report.
- Author:
Jin Hwa LEE
1
;
Yong Kyu KIM
;
Sang Joon LEE
Author Information
1. Department of plastic and Reconstructive Surgery, College of Medicine, Inje University, Seoul, Korea. psinbrain@paran.com
- Publication Type:Case Report
- Keywords:
Aplasia cutis congenita;
Cultured epithelial autograft
- MeSH:
Autografts*;
Biopsy;
Cicatrix, Hypertrophic;
Contracture;
Ectodermal Dysplasia;
Follow-Up Studies;
Groin;
Humans;
Infant;
Leg;
Skin
- From:Journal of the Korean Society of Plastic and Reconstructive Surgeons
2006;33(5):672-675
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of this study is to document the surgical methods used in infants with aplasia cutis congenita treated with allogenic dermal matrix and cultured epithelial autografts. METHODS: The large defects in both lower legs were replaced with allogenic dermal matrix to avoid the postoperative hypertrophic scar contracture and a full- thickness skin biopsy was taken from right groin area simultaneously. We sent the specimen to a commercial laboratory for culture and obtained cultured epithelial autografts(Holoderm(R)) after 2 weeks, placed it over the allogenic dermal matrix. RESULTS: The skin-defected area were nearly epithelialized after 2 weeks and there were no significant problem on during 6 months follow-up. CONCLUSION: The surgical method using allogenic dermal matrix and cultured epithelial autograft provided an excellent coverage of large skin defects of infant with aplasia cutis congenita.
