Metformin for Treatment of Antipsychotic-Induced Amenorrhea in Female Schizophrenic Patients: Report of Two Cases.
- Author:
Young Sup WOO
1
;
Won Myong BAHK
Author Information
1. Department of Psychiatry, Yeouido St. Mary's Hospital, The Catholic University of Korea School of Medicine, Seoul, Korea. wmbahk@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Schizophrenia;
Antipsychotic-induced amenorrhea;
Metformin
- MeSH:
Amenorrhea*;
Antipsychotic Agents;
Female;
Female*;
Humans;
Menstruation;
Metformin*;
Schizophrenia
- From:Korean Journal of Psychopharmacology
2013;24(4):186-189
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Amenorrhea is a common adverse event in female patients treated with antipsychotics. Because amenorrhea can produce difficulties for women suffering from schizophrenia, attempts should be made to alleviate antipsychotic-induced amenorrhea. We report two cases of female schizophrenic patients whose antipsychotic-induced amenorrhea were treated with metformin. Two patients who treated with metformin resumed their menstruation within three months. There was no adverse event reported during metformin treatment. This paper presents the rationale for the use of metformin for female patients who suffered from antipsychotic-induced amenorrhea through a literature review.