Clinical Significance of Transrectal Ultrasonography and Efficacy of Dutasteride Treatment in Patients with Hemospermia.
10.5534/kja.2011.29.3.206
- Author:
Young Jung KIM
1
;
Eu Chang HWANG
;
Sun Ouck KIM
;
Seung Il JUNG
;
Taek Won KANG
;
Dong Deuk KWON
;
Kwangsung PARK
;
Soo Bang RYU
Author Information
1. Department of Urology, Chonnam National University Medical School, Gwangju, Korea. kpark@chonnam.ac.kr
- Publication Type:Original Article
- Keywords:
Hemospermia;
Ultrasound;
Transrectal;
Dutasteride
- MeSH:
Anti-Bacterial Agents;
Azasteroids;
Digital Rectal Examination;
Ejaculatory Ducts;
Hemospermia;
Humans;
Inflammation;
Male;
Prostate;
Prostate-Specific Antigen;
Seminal Vesicles;
Watchful Waiting;
Dutasteride
- From:Korean Journal of Andrology
2011;29(3):206-212
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The aims of this study were to investigate the clinical significance of transrectal ultrasonography (TRUS) and the efficacy of dutasteride (5alpha-reductase inhibitor) in patients with hemospermia. MATERIALS AND METHODS: From January 2005 to December 2008, 60 patients with hemospermia were enrolled in the study. All patients underwent a digital rectal examination and TRUS; serum prostate specific antigen was also measured. The management of hemospermia was one of the following: watchful waiting, dutasteride treatment, or antibiotics with dutasteride. RESULTS: Thirty-four patients (56.7%) had positive findings on TRUS. There were 16 cases (26.7%) of prostate calcification, 13 cases (21.7%) of ejaculatory duct cyst, 3 cases (5%) of ejaculatory duct calcification, a case of seminal vesicle inflammation, and a case of ejaculatory duct dilation. Dutasteride treatment resulted in improvement of symptoms in 87.9% (29/33) of the cases, whereas treatment with antibiotics or antibiotics with dutasteride resulted in a 100% (6/6) success rate. However, among 14 watchful waiting patients, only 3 patients (21.4%) showed an improvement of symptoms. CONCLUSIONS: This study showed that TRUS is an easy and effective method for the assessment of hemospermia, and also revealed that dutasteride could be a useful agent in the treatment of hemospermia.