Regression of Advanced Gastric MALT Lymphoma after the Eradication of Helicobacter pylori.
- Author:
Soo Kyung PARK
1
;
Hwoon Yong JUNG
;
Do Hoon KIM
;
Mi Young KIM
;
Jeong Hoon LEE
;
Kwi Sook CHOI
;
Kee Don CHOI
;
Ho June SONG
;
Gin Hyug LEE
;
Ho KIM
Author Information
1. Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. hwoonymd@gmail.com
- Publication Type:Case Report
- Keywords:
Marginal zone B-cell lymphoma;
Stomach
- MeSH:
Aged;
Biopsy;
Biopsy, Fine-Needle;
Dyspepsia;
Endoscopy;
Endoscopy, Gastrointestinal;
Female;
Helicobacter;
Helicobacter pylori;
Humans;
Lymph Nodes;
Lymphoid Tissue;
Lymphoma;
Lymphoma, B-Cell, Marginal Zone;
Positron-Emission Tomography;
Stomach;
Urease
- From:Gut and Liver
2012;6(2):270-274
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 66-year-old female presented with a 1-month history of dyspepsia. An initial upper gastrointestinal endoscopy with biopsy revealed a low-grade mucosa-associated lymphoid tissue (MALT) lymphoma. A rapid urease test was positive for Helicobacter pylori. Endoscopic ultrasound (EUS) and computed tomography (CT) revealed a 30x15-mm lymph node (LN) in the subcarinal area. Histopathologic and phenotypic analyses of the biopsy specimens obtained by EUS-guided fine-needle aspiration revealed a MALT lymphoma, and the patient was diagnosed with a stage 4E gastric MALT lymphoma. One year after H. pylori eradication, the lesion had disappeared, as demonstrated by endoscopy with biopsy, CT, fusion whole-body positron emission tomography, and EUS. Here, we describe a patient with gastric MALT lymphoma that metastasized to the mediastinal LN and regressed following H. pylori eradication.
