Thrombolytic Therapy of Pulmonary Thromboembolism in Probable Sporadic Creutzfeldt-Jakob Disease.
- Author:
Jun Young CHANG
1
;
Jin Hun JUNG
;
Young Hee CHANG
;
Sang Yun KIM
Author Information
1. Department of Neurology, Seoul National University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Sporadic CJD;
Pulmonary thromboembolism;
Intravenous thrombolysis
- MeSH:
Brain;
Cerebellar Diseases;
Creutzfeldt-Jakob Syndrome;
Encephalopathy, Bovine Spongiform;
Female;
Hemorrhage;
Humans;
Hypotension;
Pulmonary Embolism;
Thrombolytic Therapy;
Tissue Plasminogen Activator;
Vital Signs
- From:Journal of the Korean Neurological Association
2009;27(4):405-408
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The effect of intravenous recombinant tissue plasminogen activator for patients with Creutzfeldt-Jakob disease (CJD) has yet to be determined. A woman with rapidly progressive cognitive decline, cerebellar dysfunction, and extrapyramidal symptoms, diagnosed as probable sporadic CJD, was complicated with pulmonary thromboembolism and systemic hypotension. Her vital signs were restored without brain parenchymal hemorrhage after intravenous thrombolysis. The presence of diffuse brain lesions in CJD did not increase the hemorrhagic complications associated with intravenous thrombolysis, which differs from an ischemic vascular event.
