A case of acquired hemophilia detected after influenza vaccination.
- Author:
Byung Ha CHUNG
1
;
Youn Jeong KIM
;
Min Soo KIM
;
Jin Young KIM
;
Dong il SHIN
;
Yong Soo KIM
;
Byung Kee BANG
Author Information
1. Department of Internal Medicine, The Catholic Univercity of Korea, College of Medicine, Seoul, Korea. nephron@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Acquired hemophilia;
Influenza vaccination;
Factor VIII inhibitors
- MeSH:
Aged;
Autoimmune Diseases;
Cyclophosphamide;
Factor VIII;
Female;
Hematuria;
Hemophilia A*;
Hemorrhage;
Humans;
Influenza, Human*;
Postpartum Period;
Purpura;
Vaccination*
- From:Korean Journal of Medicine
2004;66(3):298-301
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acquired hemophilia is a rare disorder associated with development of factor VIII inhibitors. Acquired inhibitors against factor VIII in nonhemophilic patients are associated with various conditions, including autoimmune diseases, malignancies, the postpartum state, drug reactions. In this report, we described the case of a 65 year-old female, who developed generalized petechiae and gross hematuria due to the appearance of inhibitors against factor VIII following influenza vaccination. She was treated with steroid and cyclophosphamide but retroperitoneal hemorrhage developed, and she died.
