Clinical and Epidemiologic Study of Kawasaki Disease in Children 8 Years of Age and Older.
- Author:
Yong Won PARK
1
;
Ji Whan HAN
;
In Sook PARK
;
Chang Hwi KIM
;
Sung Ho CHA
;
Jae Sook MA
;
Tae Chan KWON
;
Sang Bum LEE
;
Chul Ho KIM
;
Heung Jae LEE
;
Yong Soo YUN
Author Information
1. Department of Pediatrics, College of Medicine, Inje University, Seoul Paik Hospital, Seoul, Korea. yongpw@hanmail.net
- Publication Type:Original Article
- Keywords:
Kawasaki disease;
Mucocutaneous lymph node syndrome;
Coronary aneurysm;
Epidemiology;
Child
- MeSH:
Aneurysm;
Child*;
Coronary Aneurysm;
Echocardiography;
Epidemiologic Studies*;
Epidemiology;
Humans;
Incidence;
Korea;
Mucocutaneous Lymph Node Syndrome*;
Myocardial Infarction;
Prevalence;
Recurrence;
Retrospective Studies;
Siblings
- From:Korean Journal of Pediatrics
2005;48(10):1139-1142
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease (KD) in children 8 years of age and older. METHODS: For the epidemiologic study of KD in Korea, data of total 15, 692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of 211 KD patients 8 years of age and older were analyzed and compared with those of the KD patients less than 8 years of age. RESULTS: 211 patients 8 years of age and older (1.3% of total KD patients) with the mean age of 9.8 years, included 142 cases aged 8-10 years, 42 cases aged 10-12 years, and 27 cases aged 12 years and older. The male-to-female ratio was 1.9: 1, the recurrence rate was 3.8%, and the prevalence of cases in sibling was zero. Coronary arterial (CA) abnormalities were detected by echocardiography in 25.4% of the cases, including 7.6% of CA aneurysm cases. There was 1 case complicated by myocardial infarction. CONCLUSION: Comparing with the data of the KD patients less than 8 years of age, data of 211 patients 8 years of age and older showed significantly higher incidences of CA abnormalities (25.4%: 19.8%) and CA aneurysms (7.6%: 4.0%).
