Effect of Midazolam, Fentanyl and Propofol for Intravenous Anesthesia in Patients Undergoing the Cardioversion.
10.4097/kjae.2001.41.3.284
- Author:
Mee Young CHUNG
1
;
Jun Seuk CHEA
;
Chang Jae KIM
;
Hee Yeol KIM
;
Eun Ju CHO
;
Hee Sang PARK
;
Byung Ho LEE
Author Information
1. Department of Anesthesiology, College of Medicine, Catholic University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Anesthetics;
fentanyl;
midazolam;
propofol;
cardioversion;
hemodynamics
- MeSH:
Amnesia;
Anesthesia;
Anesthesia, Intravenous*;
Anesthetics;
Apnea;
Arrhythmias, Cardiac;
Blood Pressure;
Consciousness;
Coronary Care Units;
Electric Countershock*;
Fentanyl*;
Heart Rate;
Hemodynamics;
Humans;
Incidence;
Midazolam*;
Propofol*;
Shock
- From:Korean Journal of Anesthesiology
2001;41(3):284-288
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Elective cardioversion is a short procedure performed under amnesia, sedation or anesthesia for the treatment of cardiac dysrhythmia. Midazolam, fentanyl and propofol on hemodynamic changes and side effects were studied. METHODS: Thirty patients scheduled for an elective cardioversion in the coronary care unit received propofol 500microgram/kg I.V., followed by a continuous infusion with 25 75microgram/kg/min until they lost consciousness as determined by cessation of response to verbal command. All patients received midazolam 0.02 mg/kg and fentanyl 2microgram/kg I.V. 5 minutes before induction. In addition, the cardiologist administrated the electric shock. Blood pressures and heart rates were measured prior to induction, after the administration of midazolam and fentanyl, after cardioversion, 5 minutes after cardioversion and recovery. The recovery time from terminating drug administration to awakening, and the total dose of propofol were recorded. Patients were observed for side effects. RESULTS: Systolic, mean, and diastolic blood pressures were significantly decreased 5 minutes after cardioversion and recovery. Heart rates were significantly decreased after cardioversion, 5 minutes after cardioversion and recovery. Recovery times were 22.1 14.9 minutes and the total dose of propofol was 0.79 0.39 mg/kg. Incidence of apnea (> 30 s) was 30%. CONCLUSIONS: We concluded that midazolam, fentanyl and propofol in patients undergoing an electric cardioversion decreased blood pressure and heart rate, but the cardiovascular status was maintained within clinically acceptable levels.
