Primary Adenosquamous Carcinoma of the Stomach.
10.5230/jkgca.2006.6.1.31
- Author:
Yong Kwon CHO
1
;
Ji Yeong AN
;
Seong Kweon HONG
;
Min Gew CHOI
;
Jae Hyung NOH
;
Tae Sung SOHN
;
Sung KIM
Author Information
1. Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea. sungkimm@smc.samsung.co.kr
- Publication Type:Original Article
- Keywords:
Gastric cancer;
Adenosquamous carcinoma;
Gastrectomy;
Prognosis
- MeSH:
Adenocarcinoma;
Carcinoma, Adenosquamous*;
Female;
Gastrectomy;
Gastric Bypass;
Humans;
Lymph Node Excision;
Lymph Nodes;
Male;
Neoplasm Metastasis;
Prognosis;
Recurrence;
Retrospective Studies;
Stomach Neoplasms;
Stomach*
- From:Journal of the Korean Gastric Cancer Association
2006;6(1):31-35
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: A primary adenosquamous carcinoma of the stomach is relatively rare, accounting for only about 0.5% of all gastric cancers. However, its histopathologic characteristics are still unclear, and the most appropriate form of therapy has not been established yet. MATERIALS AND METHODS: We retrospectively reviewed the clinicopathologic features of 8 patients with pathologically confirmed primary adenosquamous carcinomas out of 8,268 patients who underwent gastric cancer surgery at Samsung Medical Center between September 1994 and December 2004. RESULTS: The median age of the 8 patients was 49 (41~69) years, and the male : female ratio was 5 : 3. In 3 patients, the tumor was located at the mid body of the stomach, and in 5 patients, at the lower body or antrum. The tumor sizes were 2.5~8 cm. Seven patients showed metastases to the regional lymph nodes. The UICC stage distribution were: 5 stage II, 2 stage III, and 1 stage IV. In the stage IV patient, a palliative gastrojejunostomy was performed, and he died 5 months after surgery. Of the 7 patients who underwent a radical gastrectomy and adjuvant chemotheratpy, the median survival was 34 (12~66) months, 2 patients died of cancer recurrence, and 4 patients are being followed up without evidence of recurrence. CONCLUSION: As for an adenocarcinoma of the stomach, a radical gastrectomy including regional lymph node dissection and postoperative adjuvant therapy should be performed for appropriate treatment of an adenosquamous carcinoma of the stomach.
