Endoscopic Polypectomy of Small Intestinal Peutz-Jeghers Polyps with Double Balloon Enteroscopy.
- Author:
Mi Young KIM
1
;
Jeong Sik BYEON
;
Kee Don CHOI
;
Byong Duk YE
;
Dong Hoon YANG
;
Soon Man YOON
;
Kyung Jo KIM
;
Seung Jae MYUNG
;
Suk Kyun YANG
;
Jin Ho KIM
Author Information
1. Department of Internal Medicine, Ulsan University College of Medicine, Asan Medical Center, Seoul, Korea. jsbyeon@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
Peutz-Jeghers syndrome;
Double balloon enteroscopy;
Small intestine;
Polypectomy
- MeSH:
Double-Balloon Enteroscopy;
Follow-Up Studies;
Gastrointestinal Hemorrhage;
Humans;
Intestinal Polyps;
Intestine, Small;
Intussusception;
Laparotomy;
Peutz-Jeghers Syndrome;
Polyps;
Retrospective Studies
- From:Korean Journal of Gastrointestinal Endoscopy
2009;39(6):338-345
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Small intestinal polyps in patients with Peutz-Jeghers (PJ) syndrome cause therapeutic difficulties because of the necessity for repeated laparotomy. We evaluated the short-term outcomes and long-term usefulness of double balloon enteroscopy (DBE) polypectomy for treating small intestinal PJ polyps. METHODS: We retrospectively reviewed 10 patients with PJ syndrome (M:F=7:3, mean age 22.7 years) and whose small intestinal polyps were resected with DBE between January 2005 and July 2008. We analyzed their clinical, endoscopic and pathologic features, the short-term outcomes and the long-term follow-up results. RESULTS: Among 10 patients, 2 complained hematochezia and 2 presented with intussusceptions. DBE polypectomy was performed by the oral route in 4 patients, by the anal route in 1 and by both routes in 5 without significant complications, except for only one perforation. The polyps were 0.5~6 cm in size and most of them were pedunculated. The histopathology revealed hamartomatous polyps in most cases. Follow-up small bowel series was performed in 6 of 10 patients, and 3 showed remnant polyps. Two of them underwent repeated DBE polypectomy without significant complications. CONCLUSIONS: We suggest that DBE polypectomy is a useful treatment for PJ small intestinal polyps because of the good short-term outcome and the effectiveness of repeated polypectomy for the remnant or recurrent polyps.