A Case of Trousseau's Syndrome with Catastrophic Course Triggered by an Intravenous Injection.
10.4046/trd.2011.71.2.134
- Author:
Ji Yong MOON
1
;
Sa Il KIM
;
Hyunjung KWAK
;
Soon Young SONG
;
In Soon KIM
;
Sang Heon KIM
;
Tae Hyung KIM
;
Jang Won SOHN
;
Ho Joo YOON
;
Dong Ho SHIN
;
Sung Soo PARK
Author Information
1. Department of Internal Medicine, Hanil General Hospital, KEPCO Medical Foundation, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Upper Extremity Deep Vein Thrombosis;
Antiphospholipid Syndrome;
Stomach Neoplasms
- MeSH:
Antiphospholipid Syndrome;
Arm;
Biopsy;
Brachiocephalic Veins;
Central Venous Catheters;
Cerebral Infarction;
Humans;
Injections, Intravenous;
Lupus Coagulation Inhibitor;
Melena;
Middle Aged;
Stomach Neoplasms;
Thrombosis;
Upper Extremity Deep Vein Thrombosis;
Venous Thrombosis
- From:Tuberculosis and Respiratory Diseases
2011;71(2):134-138
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Trousseau's syndrome is an unexplained thrombotic event that precedes the diagnosis of an occult visceral malignancy or appears concomitantly with the tumor. Upper extremity deep vein thrombosis is prevalent in patients with a central venous catheter. Furthermore, a peripheral intravenous injection may cause upper extremity deep vein thrombosis as well. However, a deep vein thrombosis has not been reported in the form of Trousseau's syndrome with a catastrophic clinical course triggered by a single peripheral intravenous injection. A 48-year-old man presented with a swollen left arm on which he was given intravenous fluid at a local clinic due to flu symptoms. Contrast computed tomgraphy scans showed thromboses from the left distal brachial to the innominate vein. The patient developed multiple cerebral infarctions despite anticoagulation treatment. He was diagnosed with stomach cancer by endoscopic biopsy to evaluate melena and had a persistently positive lupus anticoagulant. After recurrent and multiple thromboembolic events occurred with treatment, he died on day 20.
