Fine Needle Aspiration Biopsy of a Myxoid Leiomyosarcoma with Epithelioid Features and It Metastasized to the Abdominal Wall: A Case Report.
- Author:
Lee So MAENG
1
;
Hiun Suk CHAE
;
Anhi LEE
;
Yongan CHUNG
;
Kyo Young LEE
Author Information
1. Department of Hospital Pathology, Incheon St. Mary's Hospital, The Catholic University of Korea College of Medicine, Incheon, Korea. mls1004@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Cytology;
Biopsy, fine-needle;
Uterus;
Leiomyosarcoma;
Neoplasm metastasis
- MeSH:
Abdominal Wall;
Biopsy;
Biopsy, Fine-Needle;
Chromatin;
Cytoplasm;
Epithelioid Cells;
Leiomyosarcoma;
Mitosis;
Muscle, Smooth;
Neoplasm Metastasis;
Nuclear Envelope;
Uterus
- From:Korean Journal of Pathology
2010;44(2):220-224
- CountryRepublic of Korea
- Language:English
-
Abstract:
We present the cytologic findings observed in a fine needle aspiration biopsy specimen of a rare myxoid variant of leiomyosarcoma with epithelioid features and the tumor had metastasized to the abdominal wall. The aspirate showed hypercellularity in a hemorrhagic background. Some large 3-dimensional aggregates of spindle cells were observed. Each cell had a solitary ovoid-to-elongated nucleus with finely granulated chromatin, one or two small distinct nucleoli and an irregular nuclear membrane. There were irregular fascicles of spindle cells with cigar-shaped, blunt-ended nuclei admixed with inflammatory cells. Epithelioid cells with a rather narrow, dense cytoplasmic rim and a well-defined cell border were embedded in a myxoid matrix in a cord-like and cluster arrangement. The matrix appeared as a pale green substance with sharply defined edges. There were very few mitoses. These cytologic features were the same as those of a uterine myxoid leiomyosarcoma that was surgically excised 7 years ago, and immunohistochemical staining revealed the smooth muscle origin of the tumor.
