Diagnostic Accuracy and Interobserver Agreement in Predicting the Submucosal Invasion of Colorectal Tumors Using Gross Findings, Pit Patterns, and Microvasculatures.
- Author:
Hye Jung CHOI
1
;
Bo In LEE
;
Hwang CHOI
;
Kyu Yong CHOI
;
Sang Woo KIM
;
Joo Yong SONG
;
Jeong Seon JI
;
Byung Wook KIM
Author Information
- Publication Type:Original Article
- Keywords: Colorectal neoplasms; Colonoscopy; Neoplasm staging
- MeSH: Colonoscopy; Colorectal Neoplasms; Electronics; Electrons; Endoscopy; Humans; Light; Narrow Band Imaging; Neoplasm Staging
- From:Clinical Endoscopy 2013;46(2):168-171
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: Depth of invasion is one of the most important factors for establishing treatment strategy for colorectal tumors. METHODS: Three blinded experts reviewed electronic photos and video clips of 33 early colorectal cancer-like lesions. They estimated the depth of invasion based on conventional white light endoscopy (CWE), magnifying chromoendoscopy (MCE), and magnifying narrow band imaging endoscopy (MNE). RESULTS: The lesions included nine mucosal low-grade neoplasias, 16 mucosal high grade neoplasias, and eight carcinomas with invasion to the submucosal layer or beyond. The diagnostic accuracy for submucosal invasion by CWE ranged from 67% to 82%, while those by MCE and MNE ranged from 85% to 88% and 85% to 88%, respectively. The diagnostic accuracy significantly differed between CWE and MCE (p=0.034) and between CWE and MNE (p=0.039). The kappa values for CWE, MCE, and MNE among the endoscopists were 0.564, 0.673, and 0.673, respectively. CONCLUSIONS: The estimation of submucosal invasion for early colorectal cancer-like lesions based on MCE or MNE is more accurate than CWE. MCE and MNE were demonstrated to have substantial agreement for predicting submucosal invasion.
