New Reference Data on Bone Mineral Density and the Prevalence of Osteoporosis in Korean Adults Aged 50 Years or Older: The Korea National Health and Nutrition Examination Survey 2008-2010.
10.3346/jkms.2014.29.11.1514
- Author:
Kyung Shik LEE
1
;
Su Hyun BAE
;
Seung Hwa LEE
;
Jungun LEE
;
Dong Ryul LEE
Author Information
1. Department of Family Medicine, Bundang Jesaeng Hospital, Seongnam, Korea.
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Bone Density;
Reference Values;
Osteoporosis;
Absorptiometry, Photon;
Korean
- MeSH:
Absorptiometry, Photon;
Adult;
Aged;
Asian Continental Ancestry Group;
Bone Density;
Cross-Sectional Studies;
Female;
Femur Neck/radiography;
Hip/radiography;
Humans;
Lumbar Vertebrae/radiography;
Male;
Middle Aged;
*Nutrition Surveys;
Osteoporosis/*diagnosis/epidemiology;
Prevalence;
Reference Values;
Republic of Korea
- From:Journal of Korean Medical Science
2014;29(11):1514-1522
- CountryRepublic of Korea
- Language:English
-
Abstract:
This cross-sectional study was performed to investigate the reference values for bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) and the prevalence of osteoporosis in the Korean population by applying domestic reference data. In total, 25,043 Korean adults > or =20 yr of age (11,792 men and 13,251 women) participated in the study. The BMDs of the total hip, femoral neck, and lumbar spine were measured by DXA (Discovery-W, Hologic Inc.), and subjects with a BMD - 2.5 standard deviations or lower than the mean BMD for young adults (20-29 yr old) were considered to have osteoporosis. When applying the new reference values determined in this study from Korean subjects, the overall prevalence of osteoporosis increased in men aged > or =50 yr compared with that provided by the DXA manufacturer from Japanese subjects (12.2% vs. 7.8%, P<0.001) and decreased in postmenopausal women aged > or =50 yr (32.9% vs. 38.7%, P<0.001). According to the findings of this study, use of the reference values provided by the DXA manufacturer has resulted in the underdiagnosis of osteoporosis in Korean men and the overdiagnosis of osteoporosis in Korean women. Our data will serve as valuable reference standards for the diagnosis and management for osteoporosis in the Korean population.
