Breast Cancer Arising Adjacent to an Involuting Fibroadenoma: Serial Changes in Radiologic Features.
10.4048/jbc.2015.18.3.291
- Author:
Chae Jung PARK
1
;
Eun Kyung KIM
;
Ha Young WOO
;
Hee Jung MOON
;
Jung Hyun YOON
;
Min Jung KIM
Author Information
1. Department of Radiology, Breast Cancer Clinic, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea. mines@yuhs.ac
- Publication Type:Case Report
- Keywords:
Breast neoplasms;
Fibroadenoma;
Magnetic resonance imaging;
Mammography;
Ultrasonography
- MeSH:
Adenoma;
Adult;
Biopsy;
Breast Neoplasms*;
Breast*;
Carcinoma, Ductal;
Diagnosis;
Female;
Fibroadenoma*;
Follow-Up Studies;
Humans;
Magnetic Resonance Imaging;
Mammography;
Retrospective Studies;
Ultrasonography
- From:Journal of Breast Cancer
2015;18(3):291-295
- CountryRepublic of Korea
- Language:English
-
Abstract:
Fibroadenoma is a common benign breast lesion and its malignant transformation is rare. There have been several case reports and studies that retrospectively reviewed breast cancers that arose within fibroadenomas; however, none of these studies reported serial changes in radiologic features of the cancer, including findings from mammography and ultrasound (US). We report a case of breast cancer arising adjacent to an involuting fibro adenoma in a 39-year-old woman who was undergoing serial follow-up after her fibroadenoma was diagnosed. Seven years after her diagnosis, the lesion showed evidence of coarse calcifications, a typical sign of involution. Four years later, US revealed a newly developed hypoechoic lesion with irregular margins and peripherally located calcifications adjacent to the fibroadenoma. A core biopsy was performed, and histopathological examination resulted in a diagnosis of invasive ductal carcinoma. When new suspicious features are observed in a fibroadenoma, radiologists should raise the concern for breast cancer and proceed with diagnosis and treatment accordingly.
