Unilateral Spinal Anesthesia with Hyperbaric Levobupivacaine and Bupivacaine for Lower Limb Surgery.
10.4097/kjae.2006.50.5.536
- Author:
Se Jung LEE
1
;
Keum Young SO
;
Byung Sik YU
Author Information
1. Department of Anesthesiology and Pain Medicine, Chosun University School of Medicine, Gwangju, Korea. bsbyou@chosun.ac.kr
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
bupivacaine;
levobupivacaine;
unilateral spinal anesthesia
- MeSH:
Anesthesia, Spinal*;
Bupivacaine*;
Glucose;
Hemodynamics;
Humans;
Lower Extremity*;
Needles
- From:Korean Journal of Anesthesiology
2006;50(5):536-540
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Levobupivacaine is the isolated S-enantiomer of bupivacaine and may be a favorable alternative to bupivacaine. The author evaluated the clinical efficacy of levobupivacaine relative to bupivacaine in spinal anesthesia. METHODS: The author randomly allocated 40 ASA physical status I or II patients undergoing lower limb surgery to do unilateral spinal anesthesia with 8% glucose bupivacaine 4 mg (n = 20) or 8% glucose levobupivacaine 4 mg (n = 20). Spinal anesthesia was performed at the L3-4 interspace using a 25-gauge Whitacre spinal needle. The lateral decubitus position was maintained for fifteen minutes after injection. RESULTS: Thirty minutes after injection, unilateral sensory block was present in 60% and 40% of cases, and unilateral motor block was observed in 90% and 85% in levobupivacaine and bupivacaine group, respectively. Levobupivacaine group had no differences as compared to bupivacaine group for spinal block resolution. CONCLUSIONS: It was concluded that 8% glucose levobupivacaine 4 mg and 8% glucose bupivacaine 4 mg provided similar spinal block for lower limb surgery without hemodynamic unstability.
