Severe Fever with Thrombocytopenia Syndrome.
10.3904/kjm.2014.86.3.271
- Author:
Kye Hyung KIM
1
;
Myoung Don OH
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. mdohmd@snu.ac.kr
- Publication Type:Review
- Keywords:
Severe fever with thrombocytopenia syndrome;
Phlebovirus;
Bunyavirus
- MeSH:
Animals, Domestic;
Central Nervous System;
China;
Communicable Diseases, Emerging;
Diarrhea;
Fever*;
Japan;
Leukopenia;
Multiple Organ Failure;
Orthobunyavirus;
Phlebovirus;
Republic of Korea;
Thrombocytopenia*;
Ticks;
Viruses;
Vomiting
- From:Korean Journal of Medicine
2014;86(3):271-276
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Severe fever with thrombocytopenia syndrome (SFTS) is firstly reported in China in 2011. It is an emerging infectious disease in China, Japan and South Korea. It is caused by novel bunyavirus, called SFTS virus. The vector of SFTS is Haemaphysalis longicornis tick and domesticated animals may serve as intermediate hosts. The clinical manifestations of SFTS are fever, vomiting, diarrhea, thrombocytopenia and leukopenia. In severe cases, multiple organ failure, disseminated intravascular coagulopathy, and central nervous systems manifestation are present. The case-fatality rate is 6-30%. There is no effective antiviral therapy and supportive care is the main treatment.
