A Case of Crohn? Disease Associated with Pyoderma Gangrenosum and Peripheral Arthritis.
- Author:
Eun Sang LEE
1
;
Sung Kwon BAE
;
Jung Soo SONG
;
So Young PARK
;
Won PARK
Author Information
1. Department of Internal Medicine, Inha University College of Medicine, Inchon, Korea.
- Publication Type:Case Report
- Keywords:
Peripheral arthritis;
Crohn? disease;
Pyoderma gangrenosum
- MeSH:
Abdomen;
Arthritis*;
Biopsy;
Colitis;
Colon;
Colonoscopy;
Colostomy;
Erythema Nodosum;
Humans;
Inflammation;
Inflammatory Bowel Diseases;
Joints;
Knee;
Middle Aged;
Mucous Membrane;
Pyoderma Gangrenosum*;
Pyoderma*;
Rectal Fistula;
Sacroiliitis;
Scleritis;
Skin;
Spondylarthropathies;
Spondylitis;
Ulcer;
Uveitis
- From:The Journal of the Korean Rheumatism Association
2000;7(4):415-420
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The Crohn? disease is a inflammatory bowel disease and it? symptoms are nonspecific. The extraintestinal manifestations of Crohn? disease are arthritis, pericholangitis, erythema nodosum, pyoderma gangrenosum, uveitis, episcleritis, and miscellaneous. Arthritic manifestations caused by Crohn? disease belong to seronegative spondyloarthropathies and are divided into peripheral arthritis, spondylitis, and sacroiliitis. And peripheral arthritis in Crohn? disease usually worsen with exacerbation of bowel inflammation but pyoderma gangrenosum, the most severe skin lesion, bears little relationship to the activity or extent of the colitis. A 53 year-old man presented peripheral arthritis on multiple joints and necrotizing ulcerative skin lesion on abdomen and left knee. He had undergone T-loop colostomy due to recurrent anal fistula. Colonoscopy and biopsy of colonic mucosa showed Crohn? disease. We report a case of Crohn? disease associated with pyoderma gangrenosum and peripheral arthritis with relevant review of literatures.
