Characteristics of pathogens among severe acute respiratory infection cases in Tianjin Municipality
10.19485/j.cnki.issn2096-5087.2026.07.011
- Author:
LIU Xiaochang
;
GUO Liru
;
YANG Jie
;
WU Mingkun
;
KONG Mei
;
ZHANG Peng
;
LI Xiaoyan
- Publication Type:Journal Article
- Keywords:
severe acute respiratory infection;
Mycoplasma pneumoniae;
Haemophilus influenzae;
Streptococcus pneumoniae;
characteristics
- From:
Journal of Preventive Medicine
2026;38(7):695-698
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the infection characteristics of pathogens among cases with severe acute respiratory infection (SARI) in Tianjin Municipality, so as to provide the evidence for developing regional SARI prevention and control strategies
Methods:Sputum or throat swab specimens were collected from SARI cases at six sentinel hospitals for respiratory pathogen surveillance in Tianjin Municipality from January 2024 to December 2025. A multiplex real-time PCR nucleic acid detection kit for respiratory pathogens was used to detect 14 types of SARI pathogens. Descriptive analysis was conducted to explore pathogen detection status, as well as temporal and age distribution characteristics.
Results:A total of 3 402 specimens were collected, with 1 456 pathogen-positive samples and positive detection rate of 42.80%. More positive samples were detected from October to December, with 205, 232 and 274 positive samples accounting for 38.90%, 44.87% and 51.02%, respectively. Mycoplasma pneumoniae, Haemophilus influenzae and Streptococcus pneumoniae had relatively high positive detection rates of 10.58%, 9.88% and 6.61%, respectively. The top three pathogens ranked by positive detection rate for single infection were Mycoplasma pneumoniae, influenza A virus and Haemophilus influenzae, while the top four pathogen combinations ranked by positive detection rate for mixed infection were Haemophilus influenzae combined with Mycoplasma pneumoniae, Haemophilus influenzae combined with Streptococcus pneumoniae, respiratory syncytial virus combined with Streptococcus pneumoniae, and Haemophilus influenzae combined with influenza A virus. The 0-<6 years and 6-<18 years age groups exhibited relatively high pathogen positive detection rates of 61.14% and 59.97%, respectively.
Conclusions:The predominant pathogens among SARI patients in Tianjin Municipality were Mycoplasma pneumoniae, Haemophilus influenzae and Streptococcus pneumoniae. The risk of pathogen infection was higher in autumn and winter and among population aged 0-<18 years.
- Full text:2026111209514121941天津市严重急性呼吸道感染病例病原体感染特征.pdf
