Research progress on the association between gut microbiota and common mental disorders in adolescents
10.16835/j.cnki.1000-9817.2026304
- VernacularTitle:肠道菌群与青少年常见心理障碍关联的研究进展
- Author:
GUO Lincheng, SHENG Weizhen, WANG Gengfu, SU Puyu
1
Author Information
1. Department of Maternal & Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei 231241, Anhui Province, China
- Publication Type:Journal Article
- Keywords:
Gastrointestinal tract;
Bacteria;
Mental health;
Adolescent
- From:
Chinese Journal of School Health
2026;47(10):1507-1511
- CountryChina
- Language:Chinese
-
Abstract:
Abstract:Mental health problems among adolescents have become a major public health concern, with far reaching implications for their physical and psychological development and social functioning. In order to understand the association and potential mechanisms between gut microbiota and mental disorders in adolescents, the review summarizes the characteristics of gut microbiota alterations in adolescents and the evidence linking these alterations to common mental disorders, including depression and anxiety. From the perspective of the microbiota-gut-brain axis, it further discusses the mechanisms through which the gut microbiota may influence emotional disorders, including neurotransmitter regulation, hypothalamic-pituitary-adrenal axis response, and immune and inflammatory responses, to provide a basis for insights into the mechanisms underlying the involvement of the gut microbiota in the development of mental disorders in adolescents.
- Full text:2026111108084475594肠道菌群与青少年常见心理障碍关联的研究进展.pdf