Advances in screening and preventive treatment for latent tuberculosis infection in China
10.19485/j.cnki.issn2096-5087.2026.05.001
- Author:
XIAO Xiao
;
CHEN Bin
;
LIU Qiao
;
SHEN Xin
- Publication Type:Journal Article
- Keywords:
latent tuberculosis infection;
screening;
preventive treatment;
prevention and control
- From:
Journal of Preventive Medicine
2026;38(5):433-437
- CountryChina
- Language:Chinese
-
Abstract:
Abstract:China has entered a phase of low-to-moderate tuberculosis (TB) prevalence. However, the large population with latent tuberculosis infection (LTBI) remains a key bottleneck to ending the TB epidemic. This paper reviews the policy evolution and current implementation of LTBI screening and preventive therapy in China. It also analyzes the practical challenges in current TB control. China's LTBI control policies have gradually shifted from pilot exploration to the national strategic level. In practice, China has achieved notable progress in several areas. These include independent innovation in screening technology, evidence-based optimization of short-course preventive regimens, and steady expansion of coverage. However, LTBI control still faces multiple challenges. These include low public awareness, limitations in diagnostic technology, poor adherence to preventive therapy, and a weak support system. Based on these findings, we recommend that precise screening, short-course treatment, and systematic support serve as core development directions. These efforts should promote the transition of LTBI control in China from "pilot exploration" to "routine institutional practice".
- Full text:2026111011193491045我国结核分枝杆菌潜伏感染筛查与预防性治疗进展.pdf