Pulmonary ventilation function among the high-risk population for chronic obstructive pulmonary disease in Baoshan District
10.19485/j.cnki.issn2096-5087.2026.04.014
- Author:
WU Jing
;
WAN Jinbao
;
WU Cui
;
LIU Fanghua
;
CHEN Qiuyan
;
DING Chenghui
;
WU Han
- Publication Type:Journal Article
- Keywords:
chronic obstructive pulmonary disease;
high-risk population;
pulmonary ventilation function;
influencing factor
- From:
Journal of Preventive Medicine
2026;38(4):388-393
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the current status of pulmonary ventilation function and its influencing factors among the population aged ≥35 years at high risk for chronic obstructive pulmonary disease (COPD) in Baoshan District, Shanghai Municipality, so as to provide the evidence for formulating regional COPD prevention and control strategies.
Methods:From January 2023 to July 2025, a convenience sampling method was used to recruit COPD high-risk individuals among permanent residents aged ≥35 years in Baoshan District. Demographic information including gender and age was collected through the Shanghai New Chronic Disease Integrated Information System. Height, weight, and waist circumference were measured. Pulmonary ventilation function was assessed by measuring forced expiratory volume in one second (FEV1), forced vital capacity (FVC), peak expiratory flow (PEF), peak inspiratory flow (PIF), and instantaneous forced expiratory flow at 50% of FVC (FEF50). Multivariable logistic regression model was used to analyze influencing factors for pulmonary ventilation function abnormalities among COPD high-risk population.
Results:A total of 5 763 COPD high-risk individuals were surveyed, including 2 970 males (51.54%) and 2 793 females (48.46%). The values of FEV1, FVC, FEV1/FVC, PEF, PIF, and FEF50 were (2.12±0.68) L, (2.83±0.85) L, (75.33±12.77)%, (4.58±1.93) L/s, (2.62±1.23) L/s, and (2.54±1.26) L/s, respectively. A total of 1 399 individuals (24.28%) were identified with pulmonary ventilation function abnormalities. Multivariable logistic regression analysis showed that female (OR=0.612, 95%CI: 0.526-0.713), junior college or above (OR=0.705, 95%CI: 0.516-0.962), urban residence (OR=0.477, 95%CI: 0.401-0.568), regular physical activity (OR=0.655, 95%CI: 0.575-0.745), and higher body mass index (OR=0.946, 95%CI: 0.926-0.967) were associated with a lower risk of pulmonary ventilation function abnormalities among COPD high-risk individuals. Conversely, current smoking (OR=1.356, 95%CI: 1.075-1.709), exposure to secondhand smoke (OR=1.493, 95%CI: 1.259-1.770), and exposure to famine during adolescence (OR=1.958, 95%CI: 1.046-3.665) were associated with a higher risk.
Conclusion:The overall status of pulmonary ventilation function among COPD high-risk population in Baoshan District is moderate, with a relatively high abnormality rate, which is mainly influenced by gender, educational level, region, regular physical activity, body mass index, tobacco exposure, and famine exposure.
- Full text:2026110916552075714宝山区慢性阻塞性肺疾病高危人群肺通气功能研究.pdf
