- Author:
Engku Ismail Engku-Husna
1
;
Nur Hidayah Mohd Fauzi
1
;
Nik Ahmad Zuky Nik Lah
1
;
Siti Masitah Hamzah
1
;
W Fadhlina W Adnan
1
;
Adibah Ibrahim
1
;
Noorul Balqis Che Ibrahim
2
Author Information
- Publication Type:Other Types
- Keywords: Umbilical neoplasm; Neoplasm metastasis; Endometrial neoplasms, Primary health care, Diagnostic imaging
- From:Malaysian Family Physician 2025;20(1):1-3
- CountryMalaysia
- Language:English
- Abstract: A DARK UMBILICAL NODULE IN A POSTMENOPAUSAL WOMAN: WHAT IS YOUR DIAGNOSIS?:Sister Mary Joseph’s nodule is a rare but significant clinical sign that often indicates advanced intra- abdominal malignancy. It presents as a palpable umbilical nodule and may be the first indication of an occult primary cancer. In this article, we discuss the case of a 58-year-old postmenopausal woman who presented to a primary care clinic with a darkened umbilical lesion and progressive abdominal symptoms. She was ultimately diagnosed with metastatic endometrial carcinoma. This uncommon presentation highlights the importance of a comprehensive approach to umbilical lesions in the primary care setting. Recognising this subtle sign in primary care can lead to expedited investigations and timely intervention.
- Full text:2026110420170432998A dark umbilical nodule.pdf

