Clinical Efficacy and Mechanism of Traditional Chinese Medicine Treatment of Mycoplasma pneumoniae Pneumonia in Children Based on Collateral Disease Theory： A Review
10.13422/j.cnki.syfjx.20260897
- VernacularTitle:中医药从“络病”学说治疗儿童肺炎支原体肺炎的临床疗效及作用机制研究进展
- Author:
Qiuyan WANG
1
;
Xuejun LI
1
;
Ying DING
1
;
Yibai XIONG
2
;
Yudong WANG
2
;
Yongbin YAN
1
;
Min GAO
1
;
Hongji WU
1
;
Weifang ZHANG
3
Author Information
1. School of Pediatrics，Henan University of Chinese Medicine，Zhengzhou 450000，China
2. Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences，Beijing 100700，China
3. Pediatric Hospital，The First Affiliated Hospital of Henan University of Chinese Medicine， Zhengzhou 450000，China
- Publication Type:Review
- Keywords:
Mycoplasma pneumoniae pneumonia （MPP）;
traditional Chinese medicine （TCM）;
clinical efficacy;
mechanism;
research progress
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2026;32(23):258-268
- CountryChina
- Language:Chinese
-
Abstract:
The collateral disease theory stands as one of the most instructive frameworks for elucidating the pathology of Mycoplasma pneumoniae pneumonia （MPP）. Its characteristic pathological features—toxin damaging collaterals， dysfunction of Qi collaterals， and protracted illness involving collaterals—closely align with the manifestations of cytokine storms， immune dysregulation， and chronic damage induced by M. pneumoniae （MP）. Drug-resistant MP further exacerbates these manifestations and poses challenges in clinical treatment， making it essential to clarify the intrinsic relationship between the collateral disease theory and MPP. However， existing studies still lack relevant elaboration， resulting in a gap in guidance by traditional Chinese medicine （TCM） theory in clinical practice. Considering the instructive， scientific， and necessary role of the collateral disease theory in MPP， this paper thoroughly elucidates the pathological manifestations of MPP and the core evolutionary characteristics of collateral damage， and further provides a scientific interpretation from the perspective of collateral disease on the clinical efficacy and mechanism of TCM treatment of MPP over the past five years. This review aims to reveal the intrinsic relationship between the collateral disease theory and MPP， enrich the scientific connotation of TCM theory， and bridge the gap in TCM theoretical guidance， thereby providing scientific research clues for TCM treatment of MPP.
