Quality of life assessment in patients diagnosed with acute pulmonary embolism
- VernacularTitle:Уушгины артерийн цочмог бүлэнт бөглөрөл оношлогдсон эмчлүүлэгчдийн амьдралын чанарын үнэлгээ
- Author:
Javzan-Orlom Dorjjugder
1
;
Munkh-Erdene Dashzeveg
2
;
Zolzaya Batbold
2
;
Altankhuyag Nergui
2
;
Amgalandari Byambabaatar
2
;
Enkh-Amgalan Tserendorj
2
;
Badamsed Tserendorj
2
;
Solongo Bandi
2
;
Tumur-Ochir Tsedev-Ochir
2
Author Information
1. School of Medicine, Mongolian National University of Medical Sciences; Third State Central Hospital
2. Third State Central Hospital
- Publication Type:Journal Article
- Keywords:
pulmonary embolism;
quality of life;
PEmb-QoL;
longitudinal study;
symptom burden
- From:Mongolian Medical Sciences
2026;217(3):11-20
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Pulmonary embolism (PE) is a potentially life-threatening condition. Although advances
in diagnostic and risk-stratification tools have reduced acute mortality, few studies have
evaluated its impact on quality of life after diagnosis.
Aim:To assess health-related quality of life in patients with acute PE during hospitalization and
three months after diagnosis using the PEmb-QoL questionnaire.
Materials and Methods:This prospective longitudinal cohort study included 83 patients with acute PE who completed
the PEmb-QoL questionnaire during hospitalization and at three-month follow-up. Six
domains were assessed: symptom frequency, activities of daily living, work-related problems,
social limitations, symptom intensity, and emotional complaints. Scores were transformed
to a 0–100 scale, with higher scores indicating poorer quality of life. Statistical analyses
were performed using SPSS 26.0. Paired scores were compared using the Wilcoxon signed
rank test, and Spearman's correlation was used to assess associations with clinical severity
indices. A linear mixed-effects model including PESI, sPESI, and age assessed whether
hospitalization PEmb-QoL scores predicted three-month outcomes. The study protocol was
approved by the Research Ethics Committee of the Mongolian National University of Medical
Sciences (Approval No. 24/-25/10-1, June 12, 2025), and written informed consent was
obtained from all participants prior to enrollment.
Results:Mean age was 62.06 ± 17.5 years, and 46.4% of participants were male. Mean scores
improved across all six domains at three months. Significant improvements were observed
in symptom frequency, work-related problems, social limitations, symptom intensity, and emotional complaints (all p<0.05). Activities of daily living did not change significantly
(p=0.332). Hospitalization PEmb-QoL scores significantly predicted three-month scores
(p<0.001), independent of PESI, sPESI, and age.
Conclusion:Quality of life improved within three months after acute PE across most PEmb-QoL domains.
Scores obtained during hospitalization predicted three-month outcomes. Early PEmb-QoL
assessment may help identify patients at risk of persistent quality-of-life impairment and
guide follow-up and rehabilitation.
- Full text:2026101821264081162MMS-2026-217(3)-11-20.pdf
