Compilation Explanation for Expert Consensus on Clinical Application of Ruyi Zhenbao Pills
10.13422/j.cnki.syfjx.20260995
- VernacularTitle:《如意珍宝丸临床应用专家共识》编制说明
- Author:
Ming CHEN
1
;
Jingling CHANG
2
;
Shangquan WANG
3
;
Gejia ZHONG
4
;
Qiang DENG
5
;
Hongxia CHEN
6
;
Qi'en LI
7
;
Yaming LIN
8
;
Zujian XU
9
;
Changkuan FU
1
;
Yu'er HU
1
;
Yanming XIE
1
;
Yuanyuan LI
1
Author Information
1. Institute of Basic Research in Clinical Medicine，China Academy of Chinese Medical Sciences，Beijing 100700，China
2. Dongzhimen Hospital，Beijing University of Chinese Medicine，Beijing 100700，China
3. Wangjing Hospital，China Academy of Chinese Medical Sciences，Beijing 100102，China
4. Beijing Hospital of Tibetan Medicine，China Tibetology Research Center，Beijing 100029，China
5. Gansu Provincial Hospital of Traditional Chinese Medicine（TCM），Lanzhou 730050，China
6. Guangdong Provincial Hospital of Chinese Medicine，Guangzhou 510120，China
7. Tibetan Medical College，Qinghai University，Xining 810016，China
8. Yunnan Provincial Hospital of TCM，Kunming 650021，China
9. The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University，Luzhou 646000，China
- Publication Type:Journal Article
- Keywords:
Ruyi Zhenbao pills;
clinical application;
expert consensus;
compilation explanation;
Tibetan medicine
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2026;32(22):209-215
- CountryChina
- Language:Chinese
-
Abstract:
The compilation explanation for the Expert Consensus on Clinical Application of Ruyi Zhenbao pills systematically expounds the formulation methods and evidence-based basis of this consensus. In response to the weak clinical application evidence and ambiguous indications of Ruyi Zhenbao pills， the Institute of Basic Research in Clinical Medicine of China Academy of Chinese Medical Sciences， Wangjing Hospital of China Academy of Chinese Medical Sciences， and Dongzhimen Hospital of Beijing University of Chinese Medicine invited 39 experts from 31 medical institutions across China to complete the compilation through multi-disciplinary collaboration. The compilation strictly adheres to the World Health Organization （WHO） guidelines for guideline development and the GRADE evidence grading system. The work process covered the construction of clinical questions （a total of 30 clinical questions were determined based on expert voting results）， evidence retrieval （covering Chinese and English databases and gray literature）， safety assessment （integrating drug monitoring data and clinical research）， and the formation of recommendation opinions and consensus suggestions （18 recommendation opinions were reached through the GRADE grid method， and 22 consensus suggestions were reached through majority voting rules）. The results show that the consensus clearly states that this medicine is suitable for knee osteoarthritis， gouty arthritis， rheumatoid arthritis， neuropathic pain， and sequelae of stroke. In terms of safety， the adverse reactions are mainly gastrointestinal reactions such as nausea， vomiting， and abdominal pain. Pregnant women and those allergic to the ingredients of this medicine are contraindicated. The compilation process underwent three rounds of expert reviews and adopted methods such as nominal group technique and Delphi method to ensure the rigor of the consensus compilation process. It provides a paradigm for the formulation of expert consensus on clinical application of Tibetan medicine through the academic promotion and dynamic revision.
