Omics Technologies for Diagnosis of Osteoarthritis and Prevention and Treatment with Traditional Chinese Medicine： A Review
10.13422/j.cnki.syfjx.20251216
- VernacularTitle:组学技术在骨关节炎发病机制及中医药防治中的研究进展
- Author:
Yi WU
1
;
Jiayi JING
1
;
Weinan LIU
1
;
Jinning TONG
1
;
Xuefeng GUAN
1
Author Information
1. Liaoning University of Traditional Chinese Medicine （TCM）， Shenyang 110847，China
- Publication Type:Journal Article
- Keywords:
osteoarthritis;
genomics;
transcriptomics;
proteomics;
metabolomics
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2026;32(21):320-329
- CountryChina
- Language:Chinese
-
Abstract:
Osteoarthritis （OA） is currently the most common type of joint degenerative disorder， typically characterized by cumulative onset at the affected sites and slow disease progression， posing a serious threat to the physical and mental health of the elderly population. Traditional Chinese medicine （TCM） has long been a hot research area in the prevention and treatment of osteoarthritis， attracting widespread attention due to its high safety and low adverse reactions. In recent years， with the continuous emergence of new research technologies and methods， significant progress has been achieved in the application of omics technologies in osteoarthritis research. Omics technologies， with their high-throughput， dynamic， and comprehensive features， provide a new technical platform for identifying biomarkers with diagnostic potential， objectifying the syndrome differentiation and treatment in TCM， and developing precise targeted therapies with TCM prescriptions. This study conducted searches in the China National Knowledge Infrastructure （CNKI） and PubMed databases， with keywords such as "osteoarthritis"，"osteoarthritis （oa）"，and "genomics" for retrieval. It classified and analyzed publications based on their specific contents to elaborate on the recent application of omics technologies in osteoarthritis research and to summarize the research progress in TCM for the prevention and treatment of osteoarthritis. This review aims to provide a basis for the diagnostic research on osteoarthritis and to offer new ideas and directions for expanding the research on TCM in preventing and treating osteoarthritis.
