Clinical Efficacy of Modified Yuejuwan in Treatment of Thyroid Cysts After Microwave Ablation
10.13422/j.cnki.syfjx.20250924
- VernacularTitle:越鞠丸加味治疗微波消融术后甲状腺囊肿的临床疗效观察
- Author:
Xiaojing YU
1
;
Ying ZHOU
2
;
Wei XING
1
;
Guolei LI
2
;
Yingying LOU
2
;
Yashi WANG
1
;
Wenmin DONG
1
Author Information
1. Graduate School of Hebei University of Chinese Medicine， Shijiazhuang 050091，China
2. The First Affiliated Hospital of Hebei University of Chinese Medicine/Hebei Provincial Hospital of Traditional Chinese Medicine， Shijiazhuang 050011，China
- Publication Type:Journal Article
- Keywords:
thyroid cyst;
microwave ablation;
modified Yuejuwan;
clinical efficacy;
safety
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2026;32(21):11-18
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the clinical efficacy of modified Yuejuwan in the treatment of thyroid cysts after microwave ablation. MethodsA total of 90 patients with thyroid cysts who met the inclusion criteria and treated in the First Affiliated Hospital of Hebei University of Chinese Medicine from September 2022 to December 2023 were randomly assigned to either the control group or the observation group， with 45 patients in each group. The control group received conventional postoperative drug treatment and was followed up regularly. The observation group was additionally administrated with modified Yuejuwan for one month and followed up regularly. The alterations in volume， thyroid function parameters ［thyroid-stimulating hormone （TSH）， free triiodothyronine （FT3）， and free thyroxine （FT4）］， quality of life scores， and clinical efficacy were monitored and compared between the two groups. Additionally， the safety profile was appraised. ResultsAfter treatment， both the observation group and the control group showed a reduction in cyst volume （P<0.05）， and the observation group exhibited a more significant reduction in cyst volume than the control group （P<0.05）. After treatment， both the observation group and the control group showed a decrease in TSH level and increases in FT3 and FT4 levels （P<0.05）， and the changes were more significant in the observation group （P<0.05）. In addition， both groups exhibited elevations in the quality of life scores （P<0.05）. Moreover， the observation group showed more increments in physiological， psychological， and social scores than the control group （P<0.05）. The total response rate of the observation group was higher than that of the control group （Z=-2.516， P<0.05）. The incidence of adverse reactions was similar between the two groups， with no statistically significant difference. ConclusionModified Yuejuwan is effective in the treatment of thyroid cysts after microwave ablation. It can promote the absorption of cysts， improve the thyroid function and quality of life， and has high safety.
