LIN Yi's Clinical Experience in Treating Triple-Negative Breast Cancer Brain Metastases Using the Method of "Consolidating the Root and Cultivating the Origin，Resolving Phlegm and Dredging Collaterals"
10.13288/j.11-2166/r.2026.19.003
- VernacularTitle:林毅运用固本培元、涤痰通络分期调治三阴性乳腺癌脑转移经验
- Author:
Guibin WANG
1
;
Shicui HONG
1
;
Xue SONG
1
;
Shengqi WANG
1
;
Honglin SITU
1
;
Li GUO
1
;
Zhuobin WEN
1
;
Author Information
1. Guangdong Provincial Hospital of Chinese Medicine，Guangzhou，510120
- Publication Type:Journal Article
- Keywords:
triple-negative breast cancer;
brain metastases;
consolidating the root and cultivating the origin;
resolving phlegm and dredging collaterals;
experience of famous doctors;
LIN Yi
- From:
Journal of Traditional Chinese Medicine
2026;67(19):2048-2052
- CountryChina
- Language:Chinese
-
Abstract:
This paper summarizes professor LIN Yi's clinical experience in treating brain metastases of triple-negative breast cancer （TNBC）. It is believed that the pathogenesis of this disease is fundamentally based on spleen and lung qi deficiency， with the binding of phlegm， stasis， and toxins acting as the critical link for disease progression， and qi stagnation serving as a major factor in its protracted course. The core therapeutic principle of "consolidating the root and cultivating the origin， resolving phlegm and dredging collaterals" is proposed. Clinically， the disease is staged into active， stable， and convalescent phases. During the active phase， characterized by spleen and lung qi deficiency alongside hyperactivity of phlegm-toxin pathogens， the treatment focuses on supplementing qi， fortifying the spleen， resolving phlegm， and dredging collaterals， utilizing the Yiqi Jiangtan Tongluo Formula （益气降痰通络方）. During the stable phase， marked by spleen deficiency， weak qi， and residual phlegm， stasis， and toxins lingering in the collaterals， the treatment aims to fortify spleen， cultivate the origin， expel pathogens， and dredge collaterals， using modified Baihua Qiling Formula （白花芪苓方）. During the convalescent phase， characterized by depletion of healthy qi， dysfunction of zang-fu （脏腑） organs， and deep-seated residual phlegm， stasis， and toxins within the brain collaterals， the treatment focuses on regulating qi movement， protecting body fluids， and applying constitution-based treatments， mostly using mild and nourishing medicinals.
