Progress of researches on toxoplasmosis control strategies based on the One Health concept
10.16250/j.32.1915.2025224
- VernacularTitle:基于全健康理念的弓形虫病防控策略研究进展
- Author:
Huijun GAO
1
;
Jing LI
1
;
Pengyao LI
2
;
Rui ZHUO
2
;
Ze NI
2
;
Bin ZHENG
2
;
Shaohong LU
2
Author Information
1. Hangzhou Medical College, Zhejiang Provincial Engineering Research Center for Novel Vaccines, Zhejiang Provincial Key Laboratory of High-Level Biosafety and Biomedical Translation, Hangzhou, Zhejiang 310013, China; Co-first authors
2. Hangzhou Medical College, Zhejiang Provincial Engineering Research Center for Novel Vaccines, Zhejiang Provincial Key Laboratory of High-Level Biosafety and Biomedical Translation, Hangzhou, Zhejiang 310013, China
- Publication Type:Journal Article
- Keywords:
Toxoplasmosis;
One Health;
Zoonosis;
Control strategy
- From:
Chinese Journal of Schistosomiasis Control
2026;38(4):354-360
- CountryChina
- Language:Chinese
-
Abstract:
Toxoplasmosis, a zoonotic disease caused by the obligate intracellular parasite Toxoplasma gondii, is widely prevalent across the world. The life cycle of T. gondii involves definitive hosts (cats and felines), intermediate hosts (humans, livestock, and wild animals), and the environment (such as soil and water). The One Health concept brings together the health of humans, animals, and the environment, with aims to pursue the optimal health outcomes through coordinated management. Management of toxoplasmosis from a One Health perspective may provide key insights into formulation of interventions for toxoplasmosis control. This article reviews the complex biological characteristics and life cycle of T. gondii, as well as the importance of felines as definitive hosts in the transmission of toxoplasmosis, analyzes the epidemiology, ecological impact and economic burden of toxoplasmosis, and discusses the bottlenecks in diagnostic and monitoring systems, environmental management technologies, and One Health interdisciplinary collaboration. In addition, toxoplasmosis control strategies are proposed based on the One Health concept, covering public health interventions, management of animal sources, multi-sector collaboration, and development of novel vaccines. These strategies provide insights into interruption of toxoplasmosis transmission and maintenance of the global public health security.
