Colchicine in the treatment of linear IgA bullous dermatosis
- VernacularTitle:Шугаман иммуноглобулин А цэврүүт дерматозын эмчилгээнд колхицин хэрэглэсэн нь
- Author:
Dulguunkharaa B
1
;
Batdelger B
1
;
Badamgarav T
2
;
Ganchimeg M
2
;
Tuvshinzaya G
2
;
Enkhchimeg M
3
;
Khandsuren B
1
Author Information
1. Department of Dermatology, School of Medicine, MNUMS
2. National Dermatology Center of Mongolia
3. Orkhon Province, Regional Diagnostic and Treatment Center
- Publication Type:Case Reports
- Keywords:
Autoimmune;
Dapsone;
Alternative
- From:
Mongolian Journal of Health Sciences
2026;94(4):161-164
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Linear IgA bullous dermatosis (LABD) is a rare autoimmune blistering disease characterized by linear deposition of immunoglobulin A along the subepidermal basement membrane zone. Although it can occur in both children and adults, the disease in pediatric patients often requires careful consideration due to challenges in differential diagnosis and variability in treatment response. Dapsone is considered the first-line treatment; however, in some cases it may be unavailable, contraindicated, or associated with adverse effects, necessitating alternative therapeutic options.
Case Presentation:In this case report, we present the clinical features, diagnostic findings, treatment course, and outcomes of a 9-year-old girl diagnosed with LABD. The combination of colchicine and systemic corticosteroids resulted in marked clinical improvement, suggesting that this regimen may be a potential alternative treatment for LABD.
- Full text:202610012316585922134_161-164_Шугаман иммуноглобулин А цэврүүт дерматозын эмчилгээнд колхицин хэрэглэсэн нь.pdf
